Archive for May, 2008

Dachshund, Werewolf, and other crazy genes

Have you ever wondered about the origin of strange and notable gene names, such as hedgehog or swiss cheese? Most of the current genetic nomenclature has meaningful origins, while other genes were named on a mere whim.
Take the above mentioned hedgehog gene discovered in the 1970s by Nobel Prize laureates Edward Lewis, Christiane NĂĽsslein-Volhard and […]


Blue Pill Anniversary

This year marks the tenth anniversary of the event that revolutionized consumer pharmaceuticals. Sadly, we are not referring to the Schweinsohr (Swine’s ear a.k.a. Gomphus clavatus), the 1998 German “Fungus of the Year” winner.

You would be getting fairly close if you’ve guessed the 1998 Nobel Prize in Physiology or Medicine awarded to Ferid Murad, […]


some like it hot - others like more protein!

This success story was provided by Felix List (graduate student at Prof. R. Sterner’s Lab; Lehrstuhl Biochemie II, Prof. Sterner; Institute of Biophysics and Physical Biochemistry; University of Regensburg)

1:Expression profile and codon quality of wt sequence
2:Expression profile and codon quality of optimized sequence
3:Protein Standard
(Expression strain: BL21 (DE3) Rosetta2, pET24a)
Background:
Sulfolobus solfataricus, a hyperthermophilic archaeon of the […]