Archive for June, 2008

E.coli codon usage optimization

How to optimize a gene for E.coli codon usage using mrgene.com’s online software tool.
The movie below explains how to optimize a gene for E.coli codon usage.


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Mr. Gene’s online tool automatically tries to eliminate DNA motifs known to hamper expression in E.coli (and other prokarya). Ribosomal entry sites, TATA-Boxes or -35 Boxes present within […]


Play the protein game!

You have spent ages protecting Earth against alien invaders and other evil fellows. Now it’s high time to leave your imaginary “Universe At War” for a while and contribute your game power to curing deadly diseases in reality. Researchers from Washington University around HHMI scientist David Baker recently provided the perfect opportunity for helpers: they […]


Calling Neanderthal

Aaargh!
Ough!
Huh-huh-grumpf… ouch!?
Well, speaking isn’t always that easy.
In Jean-Jacques Annaud’s film “Quest for Fire” a group of Palaeolithic humans travels its primeval world in search of a flame to relight their extinct fire. The film’s most startling feature is the invented language spoken by the prehistoric humans. It was created by British novelist and composer Anthony […]